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Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 4.660

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_+_19706979	30.112	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr1_-_177378801	27.263	NM_001136000 NM_001168239 NM_005158	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr1_+_181421984	23.796		LAMC2	laminin, gamma 2
chr3_-_152517204	21.413	NM_023915	GPR87	G protein-coupled receptor 87
chr12_+_13240868	17.604	NM_001423	EMP1	epithelial membrane protein 1
chr12_+_13240983	17.062		EMP1	epithelial membrane protein 1
chr12_+_13240987	17.010		EMP1	epithelial membrane protein 1
chr1_+_181422016	15.530		LAMC2	laminin, gamma 2
chr5_+_145297490	15.304		SH3RF2	SH3 domain containing ring finger 2
chr1_+_181421796	15.182	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr17_-_36996611	14.748	NM_000526	KRT14	keratin 14
chr1_+_221955876	13.957	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr18_+_59593591	13.714	NM_003784	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_-_207891264	13.601	NM_001017402	LAMB3	laminin, beta 3
chr3_+_11153778	13.296	NM_001098213	HRH1	histamine receptor H1
chr17_-_37022465	12.900	NM_005557	KRT16	keratin 16
chr6_+_47774247	12.816	NM_153838	GPR115	G protein-coupled receptor 115
chr11_+_101488380	12.663	NM_001195045	YAP1	Yes-associated protein 1
chr10_+_24795465	12.144		KIAA1217	KIAA1217
chr10_+_24795446	11.662		KIAA1217	KIAA1217
chr20_+_19903778	11.387		RIN2	Ras and Rab interactor 2
chr10_-_88720908	11.209		LOC100133190	hypothetical LOC100133190
chr12_-_51173238	11.133	NM_005554	KRT6A	keratin 6A
chr18_+_59295123	11.055	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr20_-_17487480	10.655	NM_001161705	BFSP1	beaded filament structural protein 1, filensin
chr12_-_56445653	10.385		CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1
chr15_+_38319326	10.369	NM_020168	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr19_-_43955984	10.346	NM_002307	LGALS7 LGALS7B	lectin, galactoside-binding, soluble, 7 lectin, galactoside-binding, soluble, 7B
chr11_-_65860450	10.316	NM_004292	RIN1	Ras and Rab interactor 1
chr5_+_150000394	10.299	NM_001109974 NM_007286	SYNPO	synaptopodin
chr14_-_104507862	9.974		AHNAK2	AHNAK nucleoprotein 2
chr21_+_29439768	9.843		C21orf7	chromosome 21 open reading frame 7
chr13_+_77007809	9.671	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr10_+_118177371	9.572	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr1_+_34993234	9.453	NM_005268	GJB5	gap junction protein, beta 5, 31.1kDa
chr6_-_152744143	9.410		SYNE1	spectrin repeat containing, nuclear envelope 1
chr8_+_22900863	9.269	NM_001160036	RHOBTB2	Rho-related BTB domain containing 2
chr7_+_116099648	9.244	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr6_+_41712907	8.921		MDFI	MyoD family inhibitor
chr2_+_166034402	8.697	NM_001172173	CSRNP3	cysteine-serine-rich nuclear protein 3
chr6_-_152744022	8.647		SYNE1	spectrin repeat containing, nuclear envelope 1
chr15_-_38417564	8.433		C15orf52	chromosome 15 open reading frame 52
chr11_-_117640166	8.412		MPZL2	myelin protein zero-like 2
chr3_-_150578103	8.390		TM4SF1	transmembrane 4 L six family member 1
chr3_-_48607596	8.381	NM_000094	COL7A1	collagen, type VII, alpha 1
chr1_-_94779727	8.369	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr6_+_31190505	8.323	NM_014068	PSORS1C1	psoriasis susceptibility 1 candidate 1
chr15_-_53996597	8.123	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr19_+_43486640	8.100	NM_033520	C19orf33	chromosome 19 open reading frame 33
chr17_-_7434113	7.951	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr4_-_115120251	7.904	NM_024590	ARSJ	arylsulfatase family, member J
chr11_-_117640078	7.880
chr14_+_51025604	7.845	NM_001042481	FRMD6	FERM domain containing 6
chr1_-_115682374	7.837	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr3_-_150578207	7.759	NM_014220	TM4SF1	transmembrane 4 L six family member 1
chr3_-_150578148	7.727		TM4SF1	transmembrane 4 L six family member 1
chr1_+_151270301	7.692	NM_003125	SPRR1B	small proline-rich protein 1B
chr9_-_129381086	7.641	NM_001035534	FAM129B	family with sequence similarity 129, member B
chr17_-_37034288	7.581	NM_000422	KRT17	keratin 17
chr1_-_205272619	7.538	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr3_-_150578023	7.338		TM4SF1	transmembrane 4 L six family member 1
chr20_-_35586366	7.324	NM_001167823	BLCAP	bladder cancer associated protein
chr1_-_108032645	7.260	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr17_-_24068759	7.102	NM_001144942 NM_031934	RAB34	RAB34, member RAS oncogene family
chr2_-_65447267	7.024		SPRED2	sprouty-related, EVH1 domain containing 2
chr11_-_117640196	6.949		MPZL2	myelin protein zero-like 2
chr4_+_183302105	6.846		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr19_-_52427698	6.836	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr1_+_81544432	6.811		LPHN2	latrophilin 2
chr9_+_676640	6.809
chrX_-_33139349	6.766	NM_004006	DMD	dystrophin
chr11_+_384238	6.697		PKP3	plakophilin 3
chrX_-_19598912	6.679	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr3_+_64645819	6.604		LOC100507098	hypothetical LOC100507098
chr18_+_54039818	6.539		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_65447370	6.509	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr11_-_6298284	6.460	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr19_-_56215084	6.426	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr9_-_90456824	6.360	NM_001100111	LOC286238	hypothetical protein LOC286238
chr16_-_2848106	6.336	NM_022119	PRSS22	protease, serine, 22
chr5_+_147562531	6.240	NM_001195290 NM_205841	SPINK6	serine peptidase inhibitor, Kazal type 6
chr11_+_384199	6.213	NM_007183	PKP3	plakophilin 3
chr9_-_116920232	6.207	NM_002160	TNC	tenascin C
chr11_-_117640407	6.147	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2
chr6_-_10527772	6.099	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr18_+_59705918	6.077	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr1_+_17719405	6.070		ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_+_120276386	6.043	NM_016599	MYOZ2	myozenin 2
chr11_-_128399218	6.010	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr7_+_28692122	5.954	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr13_-_85271329	5.933	NM_032229	SLITRK6	SLIT and NTRK-like family, member 6
chr2_+_113591940	5.769	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr18_+_50646616	5.767	NM_004163	RAB27B	RAB27B, member RAS oncogene family
chr5_+_36644187	5.671	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_120289735	5.616	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr19_+_43971689	5.608	NM_001042507	LGALS7B	lectin, galactoside-binding, soluble, 7B
chr1_+_185064654	5.593	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr18_+_54039779	5.586		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_27062215	5.570	NM_006142	SFN	stratifin
chr6_+_121798443	5.563	NM_000165	GJA1	gap junction protein, alpha 1, 43kDa
chr11_+_20005704	5.545		NAV2	neuron navigator 2
chr2_-_166359016	5.499	NM_004482	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr6_+_74462654	5.483		CD109	CD109 molecule
chr1_-_28392966	5.440	NM_001164722 NM_001164721	PTAFR	platelet-activating factor receptor
chr18_+_54039730	5.421	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_101423378	5.382	NM_001195005 NM_032930	C11orf70	chromosome 11 open reading frame 70
chr11_+_696607	5.358		EPS8L2	EPS8-like 2
chr6_-_169392771	5.349
chr5_+_145296313	5.328	NM_152550	SH3RF2	SH3 domain containing ring finger 2
chr12_-_68369322	5.243	NM_152439	BEST3	bestrophin 3
chr6_+_83129641	5.200	NM_006670	TPBG	trophoblast glycoprotein
chr13_-_35327798	5.095	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1
chr5_-_1935764	5.040	NM_016358	IRX4	iroquois homeobox 4
chr5_+_35892747	5.028	NM_002185	IL7R	interleukin 7 receptor
chr4_+_108965167	4.990	NM_001136258	SGMS2	sphingomyelin synthase 2
chr9_+_102231616	4.946	NM_001198806	C9orf30	chromosome 9 open reading frame 30
chr2_+_36777336	4.863	NM_001177969 NM_001177970 NM_001177971 NM_001177972 NM_053276	VIT	vitrin
chr7_-_42243142	4.811	NM_000168	GLI3	GLI family zinc finger 3
chr17_+_71229151	4.809		ITGB4	integrin, beta 4
chr4_+_81325447	4.788	NM_020226	PRDM8	PR domain containing 8
chr6_+_154449334	4.763	NM_001145287	OPRM1	opioid receptor, mu 1
chr9_+_5500544	4.758	NM_025239	PDCD1LG2	programmed cell death 1 ligand 2
chr3_-_11585264	4.742	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chr2_+_219180862	4.735		PLCD4	phospholipase C, delta 4
chr17_+_71229191	4.719		ITGB4	integrin, beta 4
chrX_+_99785818	4.684	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr3_+_30623376	4.632		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr13_-_37070862	4.617	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr3_+_57069508	4.614	NM_181727	SPATA12	spermatogenesis associated 12
chr16_+_56219802	4.586	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr20_+_33223434	4.577	NM_006404	PROCR	protein C receptor, endothelial
chr17_+_71229110	4.530	NM_000213 NM_001005731	ITGB4	integrin, beta 4
chr1_+_34997928	4.528	NM_153212	GJB4	gap junction protein, beta 4, 30.3kDa
chr3_-_31997738	4.494		OSBPL10	oxysterol binding protein-like 10
chr17_-_36928604	4.484	NM_002275	KRT15	keratin 15
chr12_-_51912101	4.472	NM_000966	RARG	retinoic acid receptor, gamma
chr15_+_38849450	4.445	NM_001130448	C15orf62	chromosome 15 open reading frame 62
chr7_-_104696678	4.411	NM_182691	SRPK2	SRSF protein kinase 2
chr8_-_38505331	4.379	NM_207412	C8orf86	chromosome 8 open reading frame 86
chr19_-_48661563	4.327	NM_014400	LYPD3	LY6/PLAUR domain containing 3
chr1_-_36589744	4.324
chr18_-_72336133	4.304	NM_014643	ZNF516	zinc finger protein 516
chr3_-_188936941	4.279	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr5_+_36642424	4.209		SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_+_38318528	4.160		PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_44171578	4.111	NM_001136215 NM_057090 NM_057091	ARTN	artemin
chr1_+_28637247	4.105	NM_023923	PHACTR4	phosphatase and actin regulator 4
chr16_+_70117523	4.077	NM_005769 NM_001166395	CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr4_+_35959638	4.073	NM_001136536	DTHD1	death domain containing 1
chr1_-_117554999	4.023	NM_024626	VTCN1	V-set domain containing T cell activation inhibitor 1
chr5_+_59819761	4.022		PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_73145098	4.019		RGNEF	190 kDa guanine nucleotide exchange factor
chr19_-_60573552	4.009	NM_000641	IL11	interleukin 11
chr10_-_62002672	4.006		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_87122936	4.000	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr5_-_54317102	3.968	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr1_+_35019376	3.963	NM_024009	GJB3	gap junction protein, beta 3, 31kDa
chrX_+_99786044	3.961		SRPX2	sushi-repeat containing protein, X-linked 2
chr6_+_74462485	3.925		CD109	CD109 molecule
chr1_-_221920023	3.899	NM_001143962	CAPN8	calpain 8
chr1_-_89261021	3.893	NM_018284	GBP3	guanylate binding protein 3
chr2_-_73170290	3.891		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr7_-_16811131	3.877	NM_006408	AGR2	anterior gradient homolog 2 (Xenopus laevis)
chr4_-_122304925	3.869	NM_024873	TNIP3	TNFAIP3 interacting protein 3
chr3_+_190147633	3.825		TPRG1	tumor protein p63 regulated 1
chr17_-_24069299	3.818	NM_001142624 NM_001142625 NM_001144943	RAB34	RAB34, member RAS oncogene family
chr10_+_123862430	3.809		TACC2	transforming, acidic coiled-coil containing protein 2
chr19_-_18912112	3.806	NM_001145722 NM_001145721	HOMER3	homer homolog 3 (Drosophila)
chr1_-_151804929	3.782	NM_005978	S100A2	S100 calcium binding protein A2
chr11_-_102331643	3.772	NM_002427	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr4_-_35922288	3.771	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_42243318	3.765		GLI3	GLI family zinc finger 3
chr6_-_138470160	3.746	NM_022121	PERP	PERP, TP53 apoptosis effector
chr15_-_58477407	3.744	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr1_+_24518501	3.731	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr6_-_116799548	3.688		LOC100287467	hypothetical LOC100287467
chr14_+_95792299	3.681	NM_000710	BDKRB1	bradykinin receptor B1
chr4_+_169989680	3.674	NM_001166110	PALLD	palladin, cytoskeletal associated protein
chr1_+_24518398	3.608	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr18_-_45630154	3.603		MYO5B	myosin VB
chr14_+_20537253	3.590	NM_014579	SLC39A2	solute carrier family 39 (zinc transporter), member 2
chr2_-_165406098	3.586		COBLL1	COBL-like 1
chr3_+_30622905	3.538	NM_001024847 NM_003242	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr12_+_106498763	3.522	NM_001017523	BTBD11	BTB (POZ) domain containing 11
chr6_+_12398514	3.499	NM_001168319 NM_001955	EDN1	endothelin 1
chr19_+_7859380	3.485	NM_025061	LRRC8E	leucine rich repeat containing 8 family, member E
chr4_-_74307637	3.484		ANKRD17	ankyrin repeat domain 17
chr5_-_134942346	3.483		CXCL14	chemokine (C-X-C motif) ligand 14
chr1_+_150753601	3.465	NM_019060	CRCT1	cysteine-rich C-terminal 1
chr6_+_74462630	3.445		CD109	CD109 molecule
chr2_-_142605010	3.399		LRP1B	low density lipoprotein receptor-related protein 1B
chr10_-_118022965	3.394	NM_005264	GFRA1	GDNF family receptor alpha 1
chr14_+_104218487	3.378
chr3_+_185520744	3.362	NM_004953	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr3_+_31998269	3.360	NM_001137674	ZNF860	zinc finger protein 860
chr3_+_161877640	3.351	NM_025047	ARL14	ADP-ribosylation factor-like 14
chr22_-_43986896	3.331		KIAA0930	KIAA0930
chr1_+_199130571	3.330	NM_001142569	C1orf106	chromosome 1 open reading frame 106
chr12_-_102967828	3.293		GLT8D2	glycosyltransferase 8 domain containing 2
chr4_+_74825138	3.283	NM_000584	IL8	interleukin 8

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
6.83	1.07e-03	GO:0045103	intermediate filament-based process
1.31	1.95e-03	GO:0048856	anatomical structure development
7.23	2.22e-03	GO:0045104	intermediate filament cytoskeleton organization
1.57	3.15e-03	GO:0051246	regulation of protein metabolic process
1.31	6.14e-03	GO:0048731	system development
1.61	6.26e-03	GO:0009611	response to wounding
8.69	7.47e-03	GO:0031581	hemidesmosome assembly
2.37	7.75e-03	GO:0008544	epidermis development
1.62	7.82e-03	GO:0009888	tissue development
1.27	1.03e-02	GO:0007165	signal transduction
1.47	1.30e-02	GO:0035556	intracellular signal transduction
3.58	1.45e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.58	1.45e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
3.58	1.45e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
3.58	1.45e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
3.58	1.45e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
3.58	1.45e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
3.58	1.45e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
3.58	1.45e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.54	2.72e-02	GO:0042127	regulation of cell proliferation
3.41	2.83e-02	GO:0071158	positive regulation of cell cycle arrest
1.84	4.19e-02	GO:0043086	negative regulation of catalytic activity
1.56	4.22e-02	GO:0016265	death
1.24	4.79e-02	GO:0032502	developmental process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.68	7.07e-04	GO:0000502	proteasome complex
1.43	1.18e-03	GO:0005856	cytoskeleton
3.78	8.56e-03	GO:0031093	platelet alpha granule lumen
3.70	1.10e-02	GO:0034774	secretory granule lumen
1.21	1.32e-02	GO:0071944	cell periphery
1.21	1.57e-02	GO:0005886	plasma membrane
3.55	1.76e-02	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
5.20	2.69e-02	GO:0001533	cornified envelope
3.41	2.74e-02	GO:0031983	vesicle lumen
1.30	3.42e-02	GO:0005576	extracellular region
1.44	3.93e-02	GO:0044421	extracellular region part
1.84	4.63e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.95	1.01e-02	GO:0004867	serine-type endopeptidase inhibitor activity
2.38	1.33e-02	GO:0030414	peptidase inhibitor activity
2.42	1.42e-02	GO:0004866	endopeptidase inhibitor activity
2.32	2.90e-02	GO:0061135	endopeptidase regulator activity
1.13	4.43e-02	GO:0005515	protein binding